A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 9/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2259157
A method of modulating the biological activity of a transmembrane ligand for an Elk-related receptor tyrosine kinase in a cell expressing the transmembrane ligand, comprising forming a complex between a purified and isolated oligomerized Elk-related receptor tyrosine kinase, or an isoform or an extracellular domain of the kinase, and a transmembrane ligand expressed on the cell, thereby affecting a pathway in the cell which is regulated by the transmembrane ligand.
L'invention porte sur un procédé destiné à moduler l'activité biologique d'un ligand transmembranaire pour un récepteur tyrosine-kinase type Elk dans une cellule exprimant ledit ligand transmembranaire. Le procédé consiste à former un complexe en combinant un récepteur tyrosine-kinase type Elk oligomérisé, purifié et isolé, ou une isoforme ou un domaine extracellulaire de ladite kinase, avec un ligand transmembranaire exprimé dans la cellule, ce qui permet de moduler dans ladite cellule une voie régulée par ledit ligand transmembranaire.
Holland Sacha
Mbamalu Geraldine
Pawson Tony
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Mount Sinai Hospital Corporation
LandOfFree
Oligomerized receptors which affect pathways regulated by... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Oligomerized receptors which affect pathways regulated by..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oligomerized receptors which affect pathways regulated by... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1958286