C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 21/02 (2006.01) C07K 7/06 (2006.01) C12P 21/00 (2006.01)
Patent
CA 2389233
An enzymatic synthesis and composition of .alpha.-hydroxy carboxylic acid and .alpha.-amino acid or peptide co-oligomers is disclosed wherein a residue of the .alpha.-hydroxy carboxylic acid is linked to a residue of the .alpha.- amino acid or peptide by an amide linkage. Proteolytic enzyme papain catalyzes co-oligomerization of the .alpha.-hydroxy carboxylic acid and .alpha.-amino acid. The degree and distribution of oligomerization varies upon the type and concentrations of different reaction mixtures utilized and upon the length of allowed reaction time. The resultant oligomers may be provided to ruminants as bioavailable amino acid supplements that are resistant to degradation in the rumen.
Synthèse enzymatique et composition d'acide .alpha.-hydroxycarboxylique et d'acide .alpha.-aminé ou de co-oligomères de peptides consistant à effectuer la liaison d'un résidu de l'acide .alpha.-hydroxycarboxylique et d'un résidu de l'acide .alpha.-aminé ou du peptide au moyen d'une liaison amide. La papaïne enzymatique protéolytique catalyse la co-oligomérisation de l'acide .alpha.-hydroxycarboxylique et de l'acide .alpha.-aminé. Le degré et la répartition de l'oligomérisation varient en fonction du type et des concentrations de différents mélanges réactionnels utilisés et de la longueur de la durée réactionnelle permise. On peut donner les oligomères obtenus à des ruminants en tant que compléments aminoacides biodisponibles résistant à la dégradation dans la panse.
Forciniti Daniel
Kapila Shubhender
Lorbert Stephen J.
Nam Paul K. S.
Rajesh Mathur P.
Novus International Inc.
Smart & Biggar
LandOfFree
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