Oligonucleoside alkyl or arylphosphonate derivatives capable...

Details Oligonucleoside alkyl or arylphosphonate derivatives capable... Oligonucleoside alkyl or arylphosphonate derivatives capable...

C - Chemistry, Metallurgy

07

H

195/1.12

C07H 21/04 (2006.01) C07H 21/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 1296664

OLIGONUCLEOSIDE ALKYL OR ARYLPHOSPHONATE DERIVATIVES CAPABLE OF CROSSLINKING WITH OR CLEAVING NUCLEIC ACIDS Abstract of the Disclosure A composition for inactivating a target nucleic acid which comprises an oligonucleoside alkyl or arylphosphonate analogue which is complementary to the sequence of the target nucleic acid and includes a functional group which reacts with the target nucleic acid to render the target nucleic acid inactive or nonfunctional.

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