Oligonucleotide adjuvant

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 21/00 (2006.01) A61K 39/29 (2006.01) A61K 39/39 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2289741

The invention provides oligonucleotide adjuvants useful for the generation of both a cell mediated (cytotoxic T lymphocyte) response and an antibody response to an antigen presented by the administration of a vaccine. Vaccine compositions including the adjuvant and methods of vaccination using the adjuvants are also provided.

L'invention concerne des adjuvants oligonucléotidiques utiles pour provoquer à la fois une réaction à médiation cellulaire (lymphocytes T cytotoxiques) et une réaction immunitaire à un antigène présenté par l'administration d'un vaccin. Des compositions de vaccins renfermant l'adjuvant et des procédés de vaccination employant les adjuvants sont également prévus.

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