A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/7105 (2006.01) A61P 25/28 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2683053
The invention relates to the identification of microRNAs which expression is diminished in neurodegenerative disorders. In particular, said identified microRNAs can be used for the downregulation of the beta-secretase (BACE1) in mammalian brain and hence for the treatment of Alzheimer's disease.
L'invention porte sur l'identification de microARNs dont l'expression diminue lors de troubles neurodégéneratifs. Lesdits microARNs identifiés peuvent être utilisés pour abaisser la production de la bêta-secrétase (BACE1) dans le cerveau de mammifère et donc pour le traitement de la madie d'Alzheimer.
de Strooper Bart
Hebert Sebastien
Fetherstonhaugh & Co.
Katholieke Universiteit Leuven K.u.leuven R. & D.
Vib Vzw
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