Oligonucleotide derivatives and production thereof

C - Chemistry – Metallurgy – 07 – H

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260/229.1, 195/1

C07H 21/00 (2006.01) C07H 19/00 (2006.01) C07H 19/16 (2006.01) C07H 19/20 (2006.01) G01N 33/535 (2006.01)

Patent

CA 1212914

ABSTRACT OF THE DISCLOSURE Biotin- or 2,4-dinitrophenyl-oligodeoxyribonucleotide derivative represented by the formula shown below and its prepara- tion method is disclosed: Image wherein: R is Image m and n are each 0 or a natural number; R1 is a straight or branched hydrocarbon residue; and B is a base constituting the nucleotide (in which when a plural number of B exist, they may be either identical or different). This compound is useful for use as a non-radioactive affinity probe for nucleic acid or a primer.

447146

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