Oligonucleotide mediated nucleic acid recombination

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/90 (2006.01) C12N 15/09 (2006.01) C12N 15/10 (2006.01) C12P 19/34 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2320697

Methods of recombining nucleic acids, including homologous nucleic acids, are provided. Families of gene shuffling oligonucleotides and their use in recombination procedures, as well as polymerase and ligase mediated recombination methods are also provided.

La présente invention concerne des procédés de recombinaison d'acides nucléiques, notamment d'acides nucléiques homologues. En outre, cette invention concerne des familles d'oligonucléotides de réarrangement de gènes et leur utilisation dans des procédures de recombinaison, et concerne également des procédés de recombinaison induite par polymérase et ligase.

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