C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 31/70 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2130264
2130264 9317125 PCTABS00025 Oligonucleotides capable of inhibiting the production of proliferation associated proteins are provided. Oligonucleotides designed to be hybridizable with nucleic acids encoding nucleolar proteins are believed to be therapeutically useful. Certain of such oligonucleotides, hybridizable to portions of the gene coding for p120, especially the 3' untranslated region, were made and found to inhibit the synthesis of p120. The oligonucleotides of the invention are useful for the treatment of diseases characterized by hyperproliferation of cells such as malignancies, inflammatory and cardiovascular diseases. Treatment of human breast cell carcinoma, human epitheloid cervix carcinoma, human amelanotic malanoma and human renal cell carcinoma and other tumors are indicated.
Bennett Clarence Frank
Busch Harris
Busch Rose K.
Perlaky Laszlo
Saijo Yasuo
Baylor College Of Medicine
Isis Pharmaceuticals Inc.
Swabey Ogilvy Renault
LandOfFree
Oligonucleotide modulation of cell growth does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Oligonucleotide modulation of cell growth, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oligonucleotide modulation of cell growth will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1524557