Oligonucleotides containing molecular rods

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 21/00 (2006.01) C07H 21/04 (2006.01) C12N 15/09 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2494571

The invention is directed to an oligonucleotide comprising a molecular rod, wherein preferentially the molecular rod covalently connects the 3' end of a first nucleotide residue with the 5' end of a second nucleotide residue. Such oligonucleotides are highly advantageous for Real time PCR melting curve analysis.

L'invention concerne un oligonucléotide renfermant des tiges moléculaires. De préférence, la tige moléculaire relie l'extrémité 3' d'un premier résidu de nucléotide à l'extrémité 5' d'un deuxième résidu de nucléotide. De tels oligonucléotides sont très avantageux pour l'analyse de courbe de fusion PCR en temps réel.

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