A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/7125 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2286396
The present invention provides compositions and methods for the alimentary delivery of oligonucleotides in an animal, including a human. Modifications to the oligonucleotide which enhance uptake following alimentary delivery are provided.
Compositions et procédés pour l'administration par la voie digestive d'oligonucléotides à un animal, dont l'homme. La présente invention concerne des modifications apportées à ces oligonucléotides, qui favorisent l'assimilation après ingestion.
Anderson Kevin P.
Baker Brenda F.
Bennet C. Frank
Dean Nicholas M.
Draper Kenneth
Isis Pharmaceuticals Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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