C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C12N 9/02 (2006.01) C12N 9/22 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2259123
The invention relates to olignucleotides from the untranslated regions of housekeeping genes, and methods and compositions for modulating cell growth using same. Specifically it relates to the use of the untranslated regions (UTR) from housekeeping genes specifically the R1 and R2 components of ribonucleotide reductase UTR, for inhibiting tumor cell growth.
Cette invention concerne des oligonucléotides provenant des régions non traduites de gènes constitutifs, ainsi que des procédés et des compositions permettant de moduler la croissance cellulaire à l'aide de ces oligonucléotides. Cette invention concerne plus particulièrement l'utilisation des régions non traduites (UTR) de gènes constitutifs, et notamment celle des composants R1 et R2 d'UTR de réductase de ribonucléotides, dans l'inhibition de la croissance de cellules tumorales.
Wright Jim A.
Young Aiping H.
Lorus Therapeutics Inc.
Mbm Intellectual Property Law Llp
Wright Jim A.
Young Aiping H.
LandOfFree
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