C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 31/70 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2226458
The present invention discloses synthetic oligonucleotides complementary to contiguous and noncontiguous regions of the HBV RNA. Also disclosed are methods and kits for inhibiting the replication and expression of HBV, and for treating HBV infections and associated conditions.
On décrit des oligonucléotides synthétiques complémentaires de régions contiguës et non contiguës de l'ARN du VHB, ainsi que des procédés et des trousses permettant d'inhiber la réplication et l'expression du VHB, et de traiter les infections et les troubles associés qu'il provoque.
Craig J. Charles
Frank Bruce L.
Goodchild John
Jupp Raymond
Kilkuskie Robert E.
Hybridon Inc.
Idera Pharmaceuticals Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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