Oligonucleotides specific for hepatitis c virus

Details Oligonucleotides specific for hepatitis c virus Oligonucleotides specific for hepatitis c virus

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/70 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2226438

The present invention discloses synthetic oligonucleotides complementary to contiguous and non-contiguous regions of the HCV RNA. Also disclosed are methods and kits for inhibiting the replication of HCV, inhibiting the expression of HCV nucleic acid and protein, and for treating HCV infections.

On décrit des oligonucléotides synthétiques complémentaires de régions contigües et non contigües de l'ARN du virus de l'hépatite C (VHC), de même que des procédés et des trousses permettant d'inhiber la réplication du VHC, d'inhiber l'expression de l'acide nucléique et des protéines du VHC, et de traiter les infections dues au VHC.

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