C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 47/48 (2006.01) C07H 21/00 (2006.01) C07K 14/15 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/53 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2255822
The invention provides oligonucleotides which bind to retroviral nucleocapsid proteins with high affinity, molecular decoys for retroviral nucleocapsid proteins which inhibit viral replication, targeted molecules comprising high affinity oligonucleotides, assays for selecting test compounds, and related kits.
L'invention propose des oligonucléotides qui se lient à des protéines nucléocapsidiques rétrovirales à affinitée élevée, des leurres moléculaires pour les protéines nucléocapsidiques rétrovirales qui inhibent la réplication virale, des molécules cibles qui comprennent des oligonucléotides à affinité élevée et des dosages pour sélectionner les composés d'essai, ainsi que des coffrets appropriés.
Casas-Finet Jose
Fisher Robert
Fivash Matthew
Henderson Louis E.
Rein Alan
Department Of Health And Human Services The Government Of The United States Of America Represented By Th
Fetherstonhaugh & Co.
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