Oligonucleotides with activity against human...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 7/04 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2166889

The present invention features compounds and methods for inhibiting propagation of human immunodeficiency virus (HIV). Preferred HIV target sites are identified and oligonucleotides designed to hybridize to a target site are described. The preferred use of the oligonucleotides is as an anti-HIV agent to inhibit HIV propagation in a patient infected with HIV. Other uses of the present invention include detecting the presence of HIV by using the oligonucleotides as detection probes or amplification primers, and measuring the ability of an oligonucleotide to inhibit HIV propagation to evaluate its suitability as an anti-HIV agent for a phenotype of HIV or diagnose the presence of HIV in a patient.

La présente invention concerne des composés et des procédés inhibant la propagation du virus de l'immunodéficience humaine (VIH). Outre l'identification des sites cibles préférés du VIH, on y trouvera aussi une description des oligonucléotides conçus pour s'hybrider avec un site cible. L'application préférée des oligonucléotides est en tant qu'agent anti-VIH pour inhiber la propagation du VIH chez un patient infecté par le virus. Les autres applications de la présente invention sont les suivantes: dépistage du VIH grâce à l'utilisation d'oligonucléotides en tant que sondes de détection ou amorces d'amplification, mesure de la capacité d'un oligonucléotide à inhiber la propagation du virus et, partant, l'évaluer en tant qu'agent anti-VIH pour un phénotype donné du VIH, ou diagnostic de la présence du virus chez un patient.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Oligonucleotides with activity against human... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Oligonucleotides with activity against human..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oligonucleotides with activity against human... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1803925

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.