Oligonucleotidic sequences able to silence the expression of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/62 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2743354

The invention concerns RNA oligonucleotide sequences or sequences that are transcribed into RNA or analogous molecules able to silence the expression of the CYCLIN D1/TROP2 chimeric mRNA and their use in the treatment and the prevention of tumors.

La présente invention concerne des séquences doligonucléotides dARN ou des séquences qui sont transcrites en ARN ou molécules analogues capables dextinction de lexpression de lARNm de la chimère CYCLINE D1/TROP2 et leur utilisation dans le traitement et la prévention de tumeurs.

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