Oligopeptide derivatives and their use in secondary cataract...

Details Oligopeptide derivatives and their use in secondary cataract... Oligopeptide derivatives and their use in secondary cataract...

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61L 27/00 (2006.01) A61L 27/24 (2006.01) C07K 5/08 (2006.01) C07K 5/09 (2006.01) C07K 5/10 (2006.01) C07K 14/78 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2139429

The invention discloses particularly compounds of formula (I) in which: X1 is a hydrogen atom, a Gly residu or an N- protective group, and X2 is a hydroxy group, a Ser residu, a Ser-Pro or Ser-Pro-Cys group or a group of formula (II), in which R1 and R2 are independently a C1-C18 alkyl group, a C3-C8 cycloalkyl group, an aryl(C1-C4)alkyl group, and R1 may be H, or R1 et R2 together and with the nitrogen atom to which they are fixed form a pyrrolidino, piperidino or piperazinyl group optionally substituted by a C1-C4 alkyl radical or a 4-hydroxypiperidino group, or one of its addition salts with a pharmaceutical acceptable acid, used for the preparation of a secondary cataract prevention drug.

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