Oligopeptide prodrugs

C - Chemistry – Metallurgy – 07 – K

Patent

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530/5.04, 530/7.

C07K 5/04 (2006.01) C07K 5/06 (2006.01) C07K 5/065 (2006.01) C07K 5/083 (2006.01) C07K 7/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1247088

OLIGOPEPTIDE PRODRUGS Abstract of the Disclosure Prodrugs are described whose structures have a oligopeptide chain which is substituted by a nucleophilic chemotherapeutic residue at the .alpha.-position. The products have increased cell membrane permeability and beneficial physico-chemical properties.

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