Oligopeptide tyrosinase inhibitors and uses thereof

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/06 (2006.01) A61K 8/64 (2006.01) A61K 38/08 (2006.01) A61Q 19/02 (2006.01) C12N 9/02 (2006.01)

Patent

CA 2728122

Disclosed are peptides that inhibit the enzymatic activity of tyrosinase, as well as formulations and methods for their use in the reduction of skin pigmentation, and methods of administering the inhibitory peptides in a topical formulation. Pep-tide sequences disclosed include KFEKKFEK and YRSRKYSSWY.

La présente invention concerne des peptides qui inhibent l'activité enzymatique de la tyrosinase, ainsi que des formulations et des procédés pour les utiliser dans la réduction de la pigmentation de la peau, et des procédés d'administration des peptides inhibiteurs dans une formulation topique. Les séquences peptidiques divulguées comprennent KFEKKFEK et YRSRKYSSWY.

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