Oligopeptides and their use for diagnostic and vaccination...

Details Oligopeptides and their use for diagnostic and vaccination... Oligopeptides and their use for diagnostic and vaccination...

C - Chemistry, Metallurgy

07

K

167/130, 530/7.0

C07K 7/06 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 39/21 (2006.01) A61K 39/395 (2006.01) C07K 7/08 (2006.01) C07K 14/16 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1340914

The invention relates to oligopeptides having utility in diagnosis of, or vaccination against AIDS and ARC, and to antibodies raised against such oligopeptides. The oligopeptides have a length of 8 to 17 amino acids. The amino acid sequence corresponds to a sequence occurring in the V3 region of gp120 and comprises the .beta.-turn sequence GPG(R) at the positions 312-314 (315), or a variant .beta.-turn sequence, and flanking sequences of at least one and preferably at least two amino acids on both sides of the .beta.-turn sequence.

579498

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