Oligoribonucleotide and ribozyme analogs with terminal 3'-3'...

Details Oligoribonucleotide and ribozyme analogs with terminal 3'-3'... Oligoribonucleotide and ribozyme analogs with terminal 3'-3'...

C - Chemistry, Metallurgy

07

H

C07H 21/02 (2006.01) A61K 31/70 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2106819

The invention relates to oligoribonucleotide analogs with terminal 3'-3' and/or 5'-5' internucleotide linkages. This modification stabilizes the molecules altered in this way, including ribozymes, without adversely altering their properties, including, where appropriate, catalytic activities.

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