C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 15/203 (2006.01) A61K 31/70 (2006.01) C08B 37/00 (2006.01)
Patent
CA 2077993
171 ABSTRACT OF THE DISCLOSURE A oligosaccharide aromatic glycoside sulfate or a physiologically acceptable salt of the same which is formed from same or different monosaccharides bonded by glycoside bonds, wherein the hydrogen atom in the hydroxyl group at the position-1 carbon atom at the terminal of the oligosaccharide is substituted with a group represented by Formula (I): - Y - (O)n - R (I) (in the formula, R represents an alkyl group having 1-18 carbon atoms, n is 0 or 1, O represents an oxygen atom, and Y represents an allylene group) and at least 10% of the remaining hydroxyl groups of the sugar subunits have been subjected to sulfated esterification; an anti-viral agent containing this oligosaccharide aromatic glycoside sulfate or physiologically acceptable salt of the same as an active component; and a oligosaccharide aromatic glycoside which functions as a production intermediate are disclosed. The anti-viral agent exhibits low toxicity and superior anti- viral activity, and is especially effective against viruses which are known to cause AIDS.
Adachi Koichiro
Ikushima Naoya
Kataoka Fusayo
Katsuraya Kaname
Nakashima Hideki
Dainippon Ink And Chemicals Inc.
Kirby Eades Gale Baker
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