C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 37/10 (2006.01) C07H 11/00 (2006.01) C08B 37/00 (2006.01)
Patent
CA 2053883
ABSTRACT OF THE DISCLOSURE Novel fractions comprising oligosaccharides having 6 to 8 saccharide units and molecular weights between 1,000 and 2,000 and a sulfur content of less than 9 weight percent, are obtained by depolymerizing heparin or heparan sulfate and fractionating the digest by size and charge. These fractions inhibit capillary endothelial cell proliferation in Vitro and are useful in the in vivo inhibition of angiogenesis.
Bergendahl Karin H. L.
D'amore Patricia
Folkman Moses J.
Johansson Rolf A.
Mattsson Jan C.
Bergendahl Karin H. L.
D'amore Patricia
Folkman Moses J.
Johansson Rolf A.
Kabi Pharmacia Ab
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