Oligosaccharide derivatives

Details Oligosaccharide derivatives Oligosaccharide derivatives

C - Chemistry, Metallurgy

07

H

167/199, 260/212

C07H 15/22 (2006.01) C08B 37/00 (2006.01) A61K 31/72 (1990.01)

Patent

CA 1307785

ABSTRACT Novel compounds with anti-proliferative and mucosa- -protective activity are obtained by sulphating trestatins with sulfur trioxide complexes such as sulfur trioxide pyridine. The compounds can be used, e.g., for the prophylaxis of arteriosclerosis, especially after bypass operations or angioplasty as well as for the therapy and prophylaxis of gastric ulcers. The compounds have the formula Image wherein n is a whole number of 1-3; R is hydrogen or a residue -SO3M and M is a cation; and in which the degree of sulphation is at least 1.

572920

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