Oligosaccharide enzyme substrates and inhibitors: method and...

Details Oligosaccharide enzyme substrates and inhibitors: method and... Oligosaccharide enzyme substrates and inhibitors: method and...

C - Chemistry, Metallurgy

12

P

C12P 19/18 (2006.01) A61K 31/70 (2006.01) C07D 211/46 (2006.01) C07D 211/94 (2006.01) C07D 335/02 (2006.01) C07H 3/00 (2006.01) C07H 5/06 (2006.01) C07H 13/00 (2006.01) C07H 15/04 (2006.01) C12N 9/12 (2006.01) C12P 19/04 (2006.01) C12P 19/26 (2006.01)

Patent

CA 2106301

Oligosaccharide compounds that are substrates and inhibitors of glycosyltransferase and glycosidase enzymes and compositions containing such compounds are disclosed. A method of glycosylation is also disclosed. An E. coli transformed with phagemid CMPSIL-1, which phagemid comprises a gene for a modified CMP-sialic acid synthetase enzyme, which transformed E. coli has the ATCC accession No. 68531 is also provided.

Composés oligosaccharides constituant des substrats et des inhibiteurs des enzymes glycosyltransférase et glycosidase et composition contenant ces composés. On décrit également un procédé de glycosylation, ainsi qu'un E. coli transformé avec du phagémide CMPSIL-1, lequel phagémide comprend un gène pour l'enzyme synthétase d'acide CMP-sialique modifiée, l'E. coli transformé ayant reçu le numéro d'enregistrement ATCC 68531.

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