Oligosaccharides, preparation method and use thereof, and...

C - Chemistry – Metallurgy – 12 – P

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C12P 19/04 (2006.01) A61K 31/702 (2006.01) A61K 31/727 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) C08B 37/10 (2006.01)

Patent

CA 2554555

The invention relates to oligosaccharides, the preparation method and use thereof, and pharmaceutical compositions containing same. More specifically, the invention relates to oligosaccharides which can be used for the treatment of cancer and, in particular, to prevent and inhibit the formation of metastases. The inventive oligosaccharides can be used, for example, during early breast, lung, prostate, colon or pancreatic cancer. The oligosaccharides can be administered subcutaneously, orally or intravenously. Moreover, said oligosaccharides can be used alone or together with other anticancer agents, e.g. cytotoxics such as docetaxel or paclitaxel.

Oligosaccharides, procédé de préparation, utilisation et compositions pharmaceutiques les renfermant. La présente invention concerne des oligosaccharides utiles pour le traitement du cancer, en particulier la prévention et l'inhibition de la formation de métastases. Ils peuvent être utilisés notamment dans un stade précoce du cancer du sein, du poumon, de la prostate, du colon ou du pancréas. Les oligosaccharides sont administrables par voie sous-cutanée, iv, per os. Ils peuvent être utilisés seuls ou en combinaison avec d'autres agents anticancéreux, notamment cytotoxiques tels que le docétaxel ou le paclitaxel.

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