Omega-conopeptides

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2416287

The invention relates to .omega.-conopeptides, derivatives or pharmaceutically acceptable salts thereof, and uses thereof, including the treatment of neurologic and psychiatric disorders, such as anticonvulsant agents, as neuroprotective agents, as cardiovascular agents or for the management of pain. The invention further relates to nucleic acid sequences encoding the conopeptides and encoding propeptides, as well as the propeptides.

La présente invention concerne des .omega.-conopeptides, des dérivés ou des sels de celles-ci acceptables sur le plan pharmaceutique, ainsi que leurs utilisations, notamment dans le traitement des troubles neurologiques et psychiatriques, comme agents anticonvulsivants, neuroprotecteurs, ou cardio-vasculaires, ou dans le traitement de la douleur. Par ailleurs, cette invention concerne des séquences d'acides nucléiques codant ces conopeptides et codant les propeptides, ainsi que lesdits propeptides.

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