Omega-guanidinoacyl-l-histidines

C - Chemistry – Metallurgy – 07 – D

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C07D 233/64 (2006.01)

Patent

CA 1076123

ABSTRACT OF THE DISCLOSURE A variety of substances are reported which alter host resistance to cocci and bacilli bacterial infections. Never- the less, because of the extreme difficulty of total eradication, and the frequent reappearance of the same strains, even after their apparently successful elimination, there is a continuing need for drugs for the treatment of coccic infections. Certain guanidinoacylhistidines are effective in inducing resistant to infections due to cocci and bacilli. These compounds are omega-guanidinoacyl-L-histidines of the formula Image - where n is 1 to 5.

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