Omp26 antigen from haemophilus influenzae

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/31 (2006.01) A61K 39/102 (2006.01) C07K 14/285 (2006.01) C07K 19/00 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2225405

A novel antigenic protein derived from the outer membrane of H.influenzae is provided. DNA sequences encoding such a protein are also provided as are vaccines comprising the protein and methods of immunising a subject against H.influenzae infection. The invention also includes methods for the prophylaxis or treatment of respiratory tract infections or otitis media, as well as methods for the detection of H.influenzae, and kits for use in such methods.

L'invention concerne une nouvelle protéine antigénique dérivée de la membrane externe de la bactérie H.influenzae. L'invention concerne également des séquences D'ADN codant une telle protéine, ainsi que des vaccins comprenant ladite protéine et des procédés permettant d'immuniser un sujet contre l'infection par H.influenzae. Des procédés de prévention ou de traitement des infections des voies respiratoires ou de l'otite moyenne, des procédés de détection de la bactérie H.influenzae, et des nécessaires utilisés pour mettre en oeuvre de tels procédés sont également décrits.

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