C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/095 (2006.01) C07K 14/22 (2006.01) C07K 16/12 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2347849
Nucleic acid and amino acid sequences of the Omp85 proteins of N. gonorrhoeae and N. meningitidis, and fragments thereof are useful in vaccine compositions, therapeutic compositions and diagnostic compositions for use in the prevention, treatment and diagnosis of non-symptomatic gonococcal infection or symptomatic disease and non-symptomatic meningococcal infection and symptomatic disease. Antibodies are developed to these proteins and also useful in the compositions and methods described herein.
L'invention concerne des séquences d'acides nucléiques et d'acides aminés de protéines de surface externe de 85 kDa (Omp85) provenant de N. gonorrhoeae et N. meningitidis, et leurs fragments, lesquelles protéines sont utiles dans des compositions de vaccins, de traitement et de diagnostic destinées à être utilisées pour la prévention, le traitement et le diagnostic des gonococcies non symptomatiques et des maladies symptomatiques. L'invention concerne aussi la mise au point d'anticorps de ces protéines, utiles également dans les compositions et méthodes précitées.
Judd Ralph C.
Manning D. Scott
Gowling Lafleur Henderson Llp
The University Of Montana
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