G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 27/447 (2006.01) C07K 1/26 (2006.01)
Patent
CA 2181136
A Capillary Electrophoresis apparatus and method are disclosed which utilize a meltable plug in an end of the capillary tube to selectively pass small ionic contaminants electrophoretically and retain macromolecular analytes against one end of the plug until the plug is melted. When this plug is melted, the analytes and thecontaminants pass through unimpeded, This permits separation of the analytes from the contaminants during electrophoretic separation and enhances instrument resolution.
Sont décrits un appareil et un procédé d'électrophorèse capillaire qui utilise un tampon fusible à une extrémité du tube capillaire pour laisser passer sélectivement de petites impuretés ioniques par voie électrophorétique et retenir des analytes macromoléculaires contre une extrémité du tampon jusqu'à fusion de ce dernier. Lorsque le tampon est fondu, les analytes et les impuretés passent sans entrave. Cela permet de séparer les analytes des impuretés pendant la séparation électrophorétique et améliore la résolution des instruments.
Applera Corporation
Perkin-Elmer Corporation
Sim & Mcburney
LandOfFree
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