Once daily dosage forms of trospium

A - Human Necessities – 61 – K

Patent

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A61K 31/46 (2006.01) A61K 9/20 (2006.01) A61K 9/24 (2006.01) A61K 9/48 (2006.01) A61K 9/56 (2006.01) A61P 13/00 (2006.01)

Patent

CA 2537103

A pharmaceutical composition of a pharmaceutically acceptable trospium salt, with upon administration to a human patient generates an average steady state blood levels of trospium with a minimum (Cmin) and maximum (Cmax) blood levels of about 0.5-2.5 ng/ml and about 2.0-6.0 ng/ml, respectively.

L'invention concerne une composition pharmaceutique d'un sel de trospium acceptable pharmaceutiquement, qui, suite à une administration à un patient humain, engendre un niveau sanguin moyen d'état stable de trospium parallèlement à des niveaux sanguins minimum (Cmin) et maximum (Cmax) allant d'environ 0,5 à 2,5 ng/ml et d'environ 2,0 à 6,0 ng/ml, respectivement.

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