Once daily formulations of tetracyclines

A - Human Necessities – 61 – K

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Details

A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01) A61K 9/24 (2006.01) A61K 9/28 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2521885

Disclosed are once-daily formulations containing tetracyclines, especially doxycycline. Such formulations are useful, for instance, for the treatment of collagenase destructive enzyme-dependent diseases, such as periodontal disease and acne, and acute and chronic inflammatory disease states, such as rosacea and arthritis.

L'invention concerne des formulations en dose quotidienne unique contenant des tétracyclines, notamment de la doxycycline. De telles formulations servent par exemple au traitement de maladies dépendant des enzymes destructrices collagénase, telles que des maladies parodontales et l'acnée, et d'états pathologiques inflammatoires sévères et chroniques tels que la rosacée et l'arthrite.

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