Once-daily oral ir/cr pramipexole formulation

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/428 (2006.01) A61J 3/07 (2006.01) A61K 9/54 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2749253

An oral once-daily pramipexole formulation, comprising an immediate-release component and a controlled-release component, is provided wherein in preferred embodiments, both the immediate-release component and the controlled-release component comprise pramipexole The formulation is preferably in the form of a coated bead A method of manufacturing said formulation is also provided.

L'invention porte sur une préparation orale de pramipéxole à prise quotidienne unique comprenant un composant à libération immédiate et un composant à libération contrôlée. Dans le mode de réalisation préféré, les deux composants contiennent du pramipéxole. La préparation se présente de préférence sous la forme d'un grain enrobé. L'invention porte également sur le procédé de fabrication de ladite préparation.

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