Onco-fetal gene, gene product and uses therefor

Details Onco-fetal gene, gene product and uses therefor Onco-fetal gene, gene product and uses therefor

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C12N 1/21 (2006.01) C12N 15/70 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2092916

2092916 9206218 PCTABS00011 The present invention provides a novel cDNA sequence (Pem), a gene product protein, and uses for this novel cDNA sequence and the Pem gene product. The DNA sequence and recombinant DNA molecules of this invention are characterized in that each codes for a novel protein having the following characteristics: (1) is expressed by T-lymphoma cells, (2) is not expressed in normal thymus, activated spleen cells, gut associated lymphoid tissue, or bone marrow, and is not detectable in adult brain, liver, large intestine or ovary, (3) is expressed in immortalized or cancerous cell lines, and (4) is expressed in embryonic development.

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