A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/76 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C12N 7/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2430495
Methods of reducing the viability of a tumor cell, infecting a neoplasm in a mammal, utilizing certain non-naturally occuring viruses are disclosed. Viral reassortants, for example reovirus reassortants, and techniques for identifying PKR-sensitive viruses are also disclosed.
L'invention concerne des méthodes de réduction de la viabilité d'une cellule tumorale, par l'infection par un virus d'un néoplasme chez un mammifère ou par le traitement d'un néoplasme chez un mammifère, au moyen de certains virus non naturels. Des réassortiments viraux, comme, par exemple des réassortiments réoviraux, et des techniques d'identification des virus sensibles à PKR sont également décrits.
Bell John C.
Brown Earl Garnet
Mbisa Jean Lutamyo
Stojdl David Francis
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
University Of Ottawa
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