Oncoprotein protein kinase

Details Oncoprotein protein kinase Oncoprotein protein kinase

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2166981

An isolated polypeptide (JNK) characterized by having a molecular weight of 46kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.

L'invention concerne un polypeptide isolé (JNK) caractérisé en ce qu'il a un poids moléculaire de 46kD déterminé par réduction de SDS-PAGE, en ce qu'il a une activité de kinase sérine et thréonine et en ce qu'il phosphoryle le domaine d'activation N-terminal de C-Jun; elle concerne aussi les chaînes polynucléotidiques et la méthode de détection de JNK. Le JNK phosphoryle le domaine d'activation N-terminal de C-Jun, qui affecte l'expression de gènes à partir de sites AP-1.

Affiliated with

Also associated with

Rating

Oncoprotein protein kinase does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Oncoprotein protein kinase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oncoprotein protein kinase will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1700793