Oncostatin m induced hematopoiesis

Details Oncostatin m induced hematopoiesis Oncostatin m induced hematopoiesis

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61K 35/28 (2006.01) C07K 14/52 (2006.01) C12N 15/19 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2178256

The present invention relates to a method of inducing proliferation and differentiation of mammalian hematopoietic stem cells by transfection and expression of the oncostatin M gene. The method also relates to a method of increasing the survival of lymphocytes exposed to cytotoxic agents or radiation by expressing oncostatin M in transfected hematopoietic stem cells.

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