One-pot process for the preparation of...

C - Chemistry – Metallurgy – 07 – K

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530/5.06

C07K 5/075 (2006.01) C07K 5/06 (2006.01)

Patent

CA 2021179

A one-pot process for the preparation of .alpha.-L-aspartyl-L- phenylalanine methyl ester hydrochloride is disclosed (.alpha.-APM(HCl)). .alpha.-APH(HCl) is an intermediate in the preparation of aspartame.

On décrit un procédé requérant une seule cuve pour la préparation de l'hydrochlorure d'ester méthylique d'–-L-aspartyl-L-phénylalanine (–-APM(HCl)). L'–-APM(HCl) sert d'intermédiaire dans la préparation de l'aspartame.

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