Onset-mitigating high-frequency nerve block

A - Human Necessities – 61 – N

Patent

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A61N 1/18 (2006.01) A61N 1/20 (2006.01) A61N 1/32 (2006.01)

Patent

CA 2703867

A method of blocking signal transmission through a nerve with reduced onset activity includes applying an HFAC to an axon of a nerve to block the transmission of signals through the axon. The method may also include applying a direct current (DC) to the axon, increasing the amplitude of the DC over time to a predetermined amplitude, applying the HFAC, and then decreasing the DC. The method may also include temporarily reducing the amplitude of the HFAC to permit the transmission of signals through the axon and subsequently increasing the amplitude to block transmission without triggering an onset response. The method may also include temporarily applying an unbalanced charge to the nerve and then balancing the charge over time.

L'invention porte sur un procédé de blocage d'une transmission de signaux par un nerf ayant une activité d'attaque réduite, qui comprend l'application d'un courant alternatif à haute fréquence (HFAC) à un axone d'un nerf pour bloquer la transmission de signaux par l'axone. Le procédé peut également comprendre l'application d'un courant continu (DC) à l'axone, l'augmentation de l'amplitude du courant continu au cours du temps jusqu'à une amplitude prédéterminée, l'application du courant alternatif à haute fréquence (HFAC) et, par la suite, la diminution du courant continu (DC). Le procédé peut également comprendre la diminution temporaire de l'amplitude du courant alternatif à haute fréquence (HFAC) pour permettre la transmission de signaux par l'axone et, ultérieurement, l'augmentation de l'amplitude pour bloquer la transmission sans déclencher de réponse d'attaque. Le procédé peut également comprendre l'application temporaire d'une charge non équilibrée au nerf et, par la suite, l'équilibrage de la charge au cours du temps.

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