Ophthalmic biomaterials and preparation thereof

Details Ophthalmic biomaterials and preparation thereof Ophthalmic biomaterials and preparation thereof

C - Chemistry, Metallurgy

08

L

C08L 83/04 (2006.01) A61F 2/14 (2006.01) C08G 81/02 (2006.01) C08J 3/24 (2006.01) C08J 5/22 (2006.01) C08L 33/26 (2006.01) G02B 1/04 (2006.01) G02C 7/04 (2006.01)

Patent

CA 2430185

A process for the manufacture of an interpenetrating polymer network biomaterial matrix composition comprising at least a first silicone polymer material and a second silicone polymer material in intimate entanglement one with the other; said process comprising:- (a) vulcanising to effect cross-linking of a vulcanisable first silicone polymer backbone precursor of the general formula (I) T-Q n-T (I) wherein n is greater than or equal to O; Q is an internal siloxane group of the formula (II) -O-Si(R1R2)- (II) wherein R1, R2 may be the same or different and selected from the group consisting of H, provided that both R1R2 are not hydrogen on the same internal silicon atom; alkoxy, alkyl, aryl, functional aryl, a crosslinked organic group linking to another silicone- based chain, or a group having an internal siloxane group of the formula III: (OSiR3R4)m R5 (III) where m is >= 0; and R3 R4 and R5 for each internal siloxane group may be the same or different selected from the group consisting of alkoxy, siloxy, alkyl, functional alkyl, aryl, functional aryl, independently H, with the proviso that not more than one of R3 R4 and R5 is H on the same silicon atom; or a crosslinked organic group linking to another silicone-based chain; T is a radical of the formula (IV); -OSiR6R7R8 (IV) 19

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