Ophthalmic composition

Details Ophthalmic composition Ophthalmic composition

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 9/06 (2006.01)

Patent

CA 2141176

An ophthalmic composition comprising a compound of the formula Image wherein R1 and R2 are each a hydrogen, a halogen, a hydroxyl, a lower alkyl or a lower alkoxy, R3 and R4 are each a hydrogen, an optionally substituted lower alkyl, an optionally substituted cycloalkyl or an optionally substituted aralkyl, or form, together with the adjacent nitrogen atom, an optionally substituted ring, X is a hydrogen, an optionally substituted lower alkyl, an optionally substituted aryl or an optionally esterified or amidized carboxyl, Y is >C=0 or >CH-0R5 wherein R5 is a hydrogen, an acyl or an optionally substituted carbamoyl, m is an integer of from 0 to 2, and n is an integer of from 1 to 6, or a salt thereof, and a method for the prevention and treatment of eye diseases, comprising administering said compound or a salt thereof.

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