C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/56 (2006.01) A61K 31/416 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61P 27/06 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2505127
This invention relates to potent potassium channel blocker compounds of Formula I or a formulation thereof for the treatment of glaucoma and other conditions which leads to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.
L'invention concerne de puissants composés inhibiteurs du canal potassique de formule (I), ou une formulation desdits composés destinée au traitement du glaucome et autres affections ayant pour conséquence une pression intraoculaire élevée dans l'oeil d'un patient. L'invention concerne également l'utilisation de ces composés pour induire un effet neuroprotecteur à l'oeil d'espèces mammaliennes, en particulier les êtres humains.
Chen Meng-Hsin
Doherty James B.
Liu Luping
Natarajan Swaminathan R.
Shen Dong-Ming
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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