Ophthalmic compositions for treating ocular hypertension

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 209/88 (2006.01) A61K 31/403 (2006.01) A61K 31/4709 (2006.01) A61P 27/06 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2583622

This invention relates to potent potassium channel blocker compounds of Formula I or a formulation thereof for the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.

L'invention concerne de puissants composés bloqueurs du canal potassium représentés par la formule (1) ou une préparation obtenue à partir de ces composés pour le traitement du glaucome et autres pathologies provoquant une augmentation de la tension intra-oculaire. Cette invention concerne également l'utilisation de tels composés à des fins neuroprotectrices de l'oeil chez les espèces mammifères, en particulier chez les humains.

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