Ophthalmic compositions for treating ocular hypertension

Details Ophthalmic compositions for treating ocular hypertension Ophthalmic compositions for treating ocular hypertension

C - Chemistry, Metallurgy

07

F

C07F 9/6558 (2006.01) A61K 31/675 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2537430

This invention relates to potent potassium channel blocker compounds of structural Formula I or a formulation thereof for the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.

L'invention a trait à des composés constituant des inhibiteurs puissants du canal potassium et représentés par la formule structurale I, ou à une formulation de ces composés pour le traitement du glaucome et d'autres affections engendrant une pression intraoculaire élevée dans l'oeil d'un patient. L'invention concerne aussi l'utilisation de ces composés pour produire un effet neuroprotecteur sur l'oeil d'espèces mammifères, en particulier l'être humain.

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