Ophthalmic compositions for treating ocular hypertension

A - Human Necessities – 61 – K

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A61K 31/215 (2006.01) A61K 31/557 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2337399

Combinations of a prostaglandin, prostaglandin derivative, a hypotensive lipid derived from a prostaglandin or prostaglandin derivative or an ophthalmologically acceptable salt thereof, a .beta.-adrenergic antagonist or an ophthalmologically acceptable salt thereof and a topical carbonic anhydrase inhibitor or an ophthalmologically acceptable salt thereof are particularly useful in the treatment of ocular hypertension and glaucoma. The combinations are characterized by an improved effect and reduced side-effects.

Des combinaisons comprenant une prostaglandine, des dérivés de prostaglandine, un lipide hypotenseur provenant d'une prostaglandine ou d'un dérivé de prostaglandine, ou un sel ophtalmologiquement acceptable de ces produits, un antagoniste .beta.-adrénergique ou un sel ophtalmologiquement acceptable de celui-ci, et un inhibiteur d'anhydrase carbonique topique ou un sel ophtalmologiquement acceptable de celui-ci, sont particulièrement utiles pour le traitement de l'hypertension oculaire et du glaucome. Ces combinaisons sont remarquables par leur efficacité améliorée et leurs effets secondaires réduits.

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