A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 47/44 (2006.01) A01N 33/12 (2006.01) A01P 1/00 (2006.01) A61L 12/12 (2006.01)
Patent
CA 2701097
The invention is directed to an ophthalmic composition comprising a disuccinate of formula (I) or a corresponding salt thereof; wherein R1 is selected from hydrogen, alkyl or -C(O)alkyl, the alkyl having one to twelve carbons and optionally one or more oxygen atoms, A is a methylene group or an oxyalkylene group, and n is from 2 to 8. The ophthalmic composition also includes a cationic antimicrobial component and a tonicity agent, wherein the tonicity agent provides for an osmolality of the composition from 200 mOs/kg to 420 mOsm/kg.
L'invention porte sur une composition ophtalmique comprenant un disuccinate représenté par la formule (I) ou un sel correspondant de celui-ci; dans laquelle R1 est sélectionné parmi hydrogène, alkyle ou -C(O)alkyle, l'alkyle ayant un à douze carbones et facultativement un ou plusieurs atomes d'oxygène, A est un groupe méthylène ou un groupe oxyalkylène, et n est de 2 à 8. La composition ophtalmique comprend également un composant antimicrobien cationique et un agent de tonicité, l'agent de tonicité fournissant une osmolalité de la composition de 200 mOs/kg à 420 mOsm/kg.
Bausch & Lomb Incorporated
Osler Hoskin & Harcourt Llp
LandOfFree
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