Ophthalmic drug delivery device

A - Human Necessities – 61 – M

Patent

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Details

A61M 35/00 (2006.01) A61F 2/00 (2006.01) A61F 9/00 (2006.01)

Patent

CA 2447802

An ophthalmic drug delivery device (10) having a first endand a second end (Figure 3), an injection port (24), a reservoir, (22), and a sleeve (26) is disclosed. The injection port is for sealingly engaging a needle (102) of a syringe (100), which isfor providing a fluid (104) comprising a pharmaceutically active agent. The reservoir is disposed within the device, is flui dly coupled to the injection port, and has an opening (25) for communicating the fluid to an outer surface of a sclera (58) of an eye (52). The sleeve is for engaging the device proximate overlapping portions of the first end and the second end for forming a generally ring-shaped three- dimensional geometry upon implantation of the device on the outer surface of the sclera. The device is useful for the treatment of a disease of the posterior segment (68) of the eye.

L'invention concerne un dispositif d'administration de m~dicament ophtalmique comprenant des premi­re et seconde extr~mit~s, un orifice d'injection, un r~servoir et un manchon. L'orifice d'injection est destin~ ~ engager de fa×on ~tanche l'aiguille d'une seringue contenant un fluide comprenant un principe actif pharmaceutique. Le r~servoir est dispos~ ~ l'int~rieur du dispositif, coupl~, en ce qui concerne le fluide, ~ l'orifice d'injection et poss­de une ouverture permettant de r~pandre le fluide sur une surface ext~rieure de la scl~rotique d'un oeil. Le manchon permet d'engager le dispositif ~ proximit~ de portions recouvrantes des premi­re et seconde extr~mit~s formant, de fa×on g~n~rale, une g~om~trie tridimensionnelle en forme d'anneau lors de l'implantation du dispositif sur la surface ext~rieure de la scl~rotique. Ce dispositif est utile pour le traitement d'une maladie du segment post~rieur de l'oeil.

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