Ophthalmic formulation with gum system

A - Human Necessities – 61 – K

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Details

A61K 9/06 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2477044

There is provided a pharmaceutical composition suitable for topical administration to an eye, the composition comprising (a) a pharmacologically effective concentration of an active agent and (b) a combination of at least two ophthalmically compatible polymers comprising a novel gum system. In preferred embodiments of the present invention, the compositions increase the retention time of the active agent in the eye, when compared to compositions with other gums or gum systems.

La présente invention concerne une composition pharmaceutique adaptée pour l'administration topique sur l'oeil, la composition comprenant (a) une concentration pharmacologiquement active d'un agent actif et (b) une combinaison d'au moins deux polymères compatibles du point de vue ophtalmique formant un nouveau système de gomme. Dans les formes de réalisation préférées de la présente invention, les compositions améliorent le temps de séjour de l'ingrédient actif dans l'oeil, comparativement aux compositions comprenant d'autres gommes ou d'autres systèmes de gomme.

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