Ophthalmic formulations comprising prednisolone acetate and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/573 (2006.01) A61K 31/7036 (2006.01) A61P 27/04 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2603902

Provided by the present invention are compositions or formulations suitable for application to a patient's eyes which utilizes a topical ophthalmically- acceptable formulation comprising a therapeutically-effective amount of an ophthalmically-active antimicrobial agent, and an ophthalmically-active anti- inflammatory or steroidal agent in combination with physiologic levels of serum electrolytes in an ophthalmic formulation for the treatment of changes in the normal eye condition. The invention also includes methods of treating patient's having an ophthalmic disease, injury or disorder, utilizing the compositions or formulations. Also provided are kits comprising the compositions or formulations and a means of applying the compositions or formulation to the patient's eyes.

La présente invention porte sur des compositions ou sur des formulations appropriées pour être instillées dans les yeux d'un patient qui utilise une formulation topique acceptable d'un point de vue ophtalmique et comprenant une quantité efficace d'un point de vue thérapeutique d'un agent antimicrobien ophtalmiquement actif et d'un agent anti-inflammatoire ou stéroïdien ophtalmiquement actif en combinaison avec des taux physiologiques d'électrolytes sériques dans une formulation ophtalmique utilisée dans le traitement des modifications de l'état normal de l'oeil. L'invention porte également sur des méthodes de traitement de patients atteints d'une maladie, lésion ou trouble ophtalmique, utilisant les compositions ou formulations de l'invention. L'invention porte également sur des kits comprenant les compositions ou formulations et sur un dispositif pour instiller dans les yeux du patient les compositions ou formulations.

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